How Vitamin B12 Triggers Acne Lesions
- Noemí Paola
- Aug 30, 2018
- 1 min read
Updated: Mar 5

Recent research has revealed that the infamous acne bacteria (P. acnes), Vitamin B12, and the skin microbiome are closely related.
The research found that when B12 is taken as a supplement, these bacteria stopped producing their own amount and instead began producing porphyrin molecules. Porphyrins can generate inflammation, and inflammation triggers acne at the beginning. Vitamin B12 alters the normal metabolic pathway and activity of the skin bacteria. Moreover, B12 supplementation can make someone with clear skin start breaking out. Evidenced by the increase in acne breakouts post vitamin B12 supplementation. When there is an elevated B12 level, it leads to an overproduction of porphyrins by P. acnes. Porphyrins can induce inflammation and acne lesions.
The Bottom Line
Too much of a good thing can be problematic. Avoid supplements with high doses of vitamin B12 (i.e., 500% daily value). For those of you that already have low-B12 levels or are vegan or vegetarians, there are different alternatives to increase these levels without having to take an oral supplement and triggering acne breakouts.
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